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See also Hemodynamic force effects, stem cells embryonic stem cells (ESC), 229230 endothelial progenitor cells (EPCs), 228229 mesenchymal stem cells (MSC), 229 stem cells uses, 237239 Vascularization, 138141 Vascular morphogenesis, 1819, 141147 Vascular niche, for adult HSC, 10 Vascular responses extracellular matrices (ECM) (see Extracellular matrices (ECM)) hypoxia-inducible factor 1 (HIF-1) angiogenesis, 113 circulating angiogenic cells (CACs), 113114 ischemic preconditioning (IPC), 115 Vascular tube morphogenesis and stabilization, molecular control blood vessel assembly, in 3D matrices, 3335 Cdc42 coupling, cell polarity pathways, 2425 and Rac1, 23 collagen type IV, in EC-pericyte tube coassembly and maturation events, 40 cytokines, 4243 in 3D extracellular matrices Cdc42 and MT1-MMP, 2829 components, differential effects of, 1920 and vascular morphogenesis, 1819 and EC lumen signaling complex, definition of, 2931 sprouting, molecular events, 2022 upregulation of, and pericyte integrins, 4142 vascular guidance tunnels, 3335 fibronectin matrix assembly, 3940 MMPs role, vascular tube regression responses, 3133 MT1-MMP in 3D collagen matrices, 2527 physical spaces, network formation, 2728 Pak activation events, 2324 Pak-2 and Pak-4, 23 pericyte EC-lined tube networks, molecular mechanisms, 3537 ECM remodeling events and basement membrane matrix assembly, 3739 recruitment, vascular guidance tunnels, 35 TIMP-3, basement membrane matrix assembly, 4041 PKCe and Src,in EC tube morphogenesis, 2324 Rho GTPases, 2223 Vasculature regulation, O2 and ECM.

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